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Antigenic Specificity | GRM4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibit |
Immunogen | Immunogen: Recombinant protein of human GRM4 (NP 000832.1). |
Other Names | [metabotropic glutamate receptor 4 isoform 1; Metabotropic glutamate receptor 4; metabotropic glutamate receptor 4; glutamate metabotropic receptor 4] |
Gene, Accession # | [GRM4], Gene ID: 2914, NCBI: NP_000832.1, UniProt: Q14833 |
Catalog # | MBS8573318 |
Price | $280 |
Order / More Info | GRM4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |