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Antigenic Specificity | AGTR1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Angiotensin II (Ang II), the main effector molecule of the renin-angiotensin system, exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1, also named as AT1R), thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone, cardiovascular function, salt and water homeostasis, AGTR1 exerts an indispensable physiological role. AGTR1 has been implicated in diverse aspects of human disease, from the regulation of blood pressure and cardiovascular homeostasis to cancer progression. |
Immunogen | Immunogen: Fusion Protein of AGTR1 |
Other Names | [AG2S; AGTR1; AGTR1A; AGTR1B; Angiotensin II type 1 receptor; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; AT2R1A; AT2R1B; HAT1R; Type 1 angiotensin II receptor] |
Gene, Accession # | [AGTR1], Gene ID: 185, NCBI: BC022447, UniProt: P30556 |
Catalog # | MBS2549033 |
Price | $220, $290, $435 |
Order / More Info | AGTR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |