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Antigenic Specificity | TRAF6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRAFs (TNF receptor associated proteins) form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF receptor superfamily and the interleukin 1 receptor. The carboxy terminal region of TRAFs is required for self association and interaction with receptor cytoplasmic domains following ligand induced oligomerization. Recent molecular cloning studies have lead to identification of six TRAFs (TRAF1 TRAF6). Recently it has been shown that TRANCE/OPGL activates the antiapoptotic serine/threonine kinase Akt/PKB through a signaling complex involving c Src and TRAF6. Mice deficient in TRAF6 are osteopetrotic with defects in bone remodeling and tooth eruption due to impaired osteoclast function. Like TRA |
Immunogen | Immunogen: TRAF6 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 436 of rat TRAF6 as the immunogen. |
Other Names | [Rabbit TRAF6; TRAF6; TRAF6; TRAF-6; TNF receptor associated protein 6; TRAF6; TRAF 6; TRAF-6; TRAF 6; TRAF-6] |
Gene, Accession # | [TRAF6], Gene ID: 100862757, NCBI: NP_001243915.1 |
Catalog # | MBS5309139 |
Price | $705 |
Order / More Info | TRAF6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |