TRAF6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRAF6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration500 ug/ml
ApplicationsWestern Blot (WB)
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DescriptionTRAFs (TNF receptor associated proteins) form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF receptor superfamily and the interleukin 1 receptor. The carboxy terminal region of TRAFs is required for self association and interaction with receptor cytoplasmic domains following ligand induced oligomerization. Recent molecular cloning studies have lead to identification of six TRAFs (TRAF1 TRAF6). Recently it has been shown that TRANCE/OPGL activates the antiapoptotic serine/threonine kinase Akt/PKB through a signaling complex involving c Src and TRAF6. Mice deficient in TRAF6 are osteopetrotic with defects in bone remodeling and tooth eruption due to impaired osteoclast function. Like TRA
ImmunogenImmunogen: TRAF6 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 436 of rat TRAF6 as the immunogen.
Other Names[Rabbit TRAF6; TRAF6; TRAF6; TRAF-6; TNF receptor associated protein 6; TRAF6; TRAF 6; TRAF-6; TRAF 6; TRAF-6]
Gene, Accession #[TRAF6], Gene ID: 100862757, NCBI: NP_001243915.1
Catalog #MBS5309139
Price$705
Order / More InfoTRAF6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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