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Antigenic Specificity | CKII alpha prime polypeptide |
Clone | [5F9-H11-F7] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: Casein kinase II (CK2) is a constitutively active, ubiquitously expressed serine/threonine protein kinase that is thought to have a regulatory function in cell proliferation, cell differentiation and apoptosis. CK2 functions as a tetrameric complex consisting of two regulatory beta-subunits and two catalytic units (alpha and alpha') in a homomeric or heteromeric conformation. Whilst the alpha- and alpha'-subunits are catalytically identical, proteins that regulate CK2, such as cdc2 and Hsp90, preferentially bind to the alpha and not the alpha'-subunit. CK2 can phosphorylate a number of key intracellular signaling proteins implicated in tumor suppression (p53 and PTEN) and tumorigenesis (myc, jun, NF-kappaB). CK2 is also thou |
Immunogen | Immunogen: Purified recombinant fragment of human CSNK2A2 (AA: 194-350) expressed in E Coli. Sequence Similarities: Contains 1 protein kinase domain. |
Other Names | [Casein kinase 2 alpha prime polypeptide; Casein kinase II alpha chain; Casein kinase II subunit alpha; CK II alpha; CK II; CK2A2; CKII; CSK22_HUMAN; CSNK2A1; CSNK2A2; FLJ43934], [CSNK2A2; CK2A2; CSNK2A1] |
Gene, Accession # | [CK2alpha], Gene ID: 1459, NCBI: NP_001887.1, UniProt: P19784 |
Catalog # | MBS476342 |
Price | $335 |
Order / More Info | CKII alpha prime polypeptide Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |