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Antigenic Specificity | MSK1 (Phospho Ser376) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MSK1 (S376) Polyclonal Antibody detects endogenous levels of MSK1 protein only when phosphorylated at S376. MSK-1 is a mitogen and stress activated protein kinase-1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK-1can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG-14 in response to mitogen and stress. Similar to RSK, MSK-1 contains two kinase domains (N-term and a C-term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK-1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C-terminal |
Immunogen | Immunogen: Synthesized peptide derived from human MSK1 around the phosphorylation site of S376 |
Other Names | [Rabbit MSK1 (phospho Ser376); RPS6KA5; MSK1; Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen-and stress-activated protein kinase 1; RSK-like protein kinase; RSKL] |
Gene, Accession # | [MSK1], Gene ID: 9252, NCBI: NP_004746.2, UniProt: O75582 |
Catalog # | MBS9701188 |
Price | $130, $220, $325 |
Order / More Info | MSK1 (Phospho Ser376) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |