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Antigenic Specificity | RAC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteocla |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human RAC1 (NP 008839.2). |
Other Names | [MIG5; MRD48; Rac-1; TC-25; p21-Rac1] |
Gene, Accession # | [RAC1], Gene ID: 5879, NCBI: P63000.1, UniProt: P63000 |
Catalog # | MBS8546987 |
Price | $280 |
Order / More Info | RAC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |