CD86 (C-term), 269-298 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD86 (C-term), 269-298
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis CD86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human CD86. This gene encodes a type I membrane protein that is amember of the immunoglobulin superfamily. This protein is expressedby antigen-presenting cells, and it is the ligand for two proteinsat the cell surface of T cells, CD28 antigen and cytotoxicT-lymphocyte-associated protein 4. Binding of this protein withCD28 antigen is a costimulatory signal for activation of theT-cell. Binding of this protein with cytotoxicT-lymphocyte-associated protein 4 negatively regulates T-cellactivation and diminishes the immune response. Alternative splicingresults
Immunogenn/a
Other Names[T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B72; FUN-1; CD86; CD86; CD28LG2]
Gene, Accession #[CD86], Gene ID: 942, NCBI: NP_001193853.1, UniProt: P42081
Catalog #MBS9204844
Price$165, $370
Order / More InfoCD86 (C-term), 269-298 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLiu, Y., et al. Hum. Immunol. 71(11):1141-1146(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Grujic, M., et al. J. Immunol. 185(3):1730-1743(2010) Dalla-Costa, R., et al. Hum. Immunol. 71(8):809-817(2010) Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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