Edit |   |
---|---|
Antigenic Specificity | Human GSK-3b |
Clone | [5D6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA; Immunoprecipitation; Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human GSK-3 beta. Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3 alpha and GSK-3 beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility. |
Immunogen | n/a |
Other Names | [Mouse Human GSK-3b - Purified, Unlabeled; Mouse Human GSK-3 beta], [GSK3B; GSK3B; GSK3B] |
Gene, Accession # | Gene ID: 2932, NCBI: NP_001139628.1, UniProt: P49841 |
Catalog # | MBS670121 |
Price | $385 |
Order / More Info | Human GSK-3b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |