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Antigenic Specificity | USP46 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: USP46 antibody detects endogenous levels of total USP46. Function: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).Subunit Structure: Interacts with WDR48 (PubMed:19075014, PubMed:26388029). Interacts with WDR20 (PubMed:20147737).Similarity: Belongs to the peptidase C19 family. USP12/USP46 subfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human USP46 Tissue Specificity: Broadly expressed. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (100%), Zebrafish (80%), Bovine (100%), Horse (92%), Sheep (100%), Dog (100%), Chicken (100%) |
Other Names | [Deubiquitinating enzyme 46; FLJ11850; FLJ12552; FLJ14283; FLJ39393; Ubiquitin carboxyl terminal hydrolase 46; Ubiquitin carboxyl-terminal hydrolase 46; Ubiquitin specific peptidase 46; Ubiquitin specific processing protease 46; Ubiquitin specific protease 46; Ubiquitin thioesterase 46; Ubiquitin thiolesterase 46; Ubiquitin-specific-processing protease 46; UBP46_HUMAN; USP46] |
Gene, Accession # | [USP46], Gene ID: 64854, NCBI: NP_001127695.1, UniProt: P62068 |
Catalog # | MBS9610306 |
Price | $240, $280 |
Order / More Info | USP46 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |