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Antigenic Specificity | Human RRM2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | gorilla, human, orangutan. predicted reactivity: monkey (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: synthetic peptide (GDPERPEAAGLDQDER) corresponding to amino acids 2 to 17 of human p53R2. The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and g-irradiation that cause DNA damages. |
Immunogen | Immunogen Description: Synthetic peptide from human RRM2B / p53R2. Percent identity by BLAST analysis: Human, Gorilla, Orangutan (100%); Monkey, Marmoset (94%); Horse (81%). |
Other Names | [RRM2B (aa2-17) IHC-plus; RRM2B; MTDPS8A; MTDPS8B; p53R2; PEOA5; Human RRM2B], [RRM2B; RRM2B; P53R2; MTDPS8A; MTDPS8B; P53R2; p53R2] |
Gene, Accession # | [RRM2B], Gene ID: 50484, NCBI: NP_056528.2, UniProt: Q7LG56 |
Catalog # | MBS240378 |
Price | $660 |
Order / More Info | Human RRM2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |