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Antigenic Specificity | Mouse DELTA-LIKE PROTEIN 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (weak) |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognises mouse Delta-like protein 3 (DLL3), one of the five major ligands of the Notch signalling pathway, which is activated through the binding of specific ligands to the Notch receptors Notch 1-4.. . The Notch signalling pathway is an evolutionarily conserved pathway in multi-cellular organisms, which is vital for cell-cell communication, important during fundamental developmental and physiological processes, including regulation of cell fate decisions during neuronal, cardiac and endocrine development, stem cell haematopoiesis, thymic T-cell development, and both tumour progression and suppression. . . Ligation of Notch receptors by their specific ligands, Jagged1 (CD339), Jagged2, Delta like-1 (DLL1), DLL3 and DLL4, |
Immunogen | Immunogen: Keyhole Limpet Hemocyanin (KLH) conjugated peptide sequence CSPEHGYCEEPDE, corresponding to amino acids 222-234 of mouse DLL3. Buffer Solution: Phosphate buffered saline. Antiserum Preparation: Antiserum to mouse DLL3 was raised by repeated immunisation of rabbits with protein peptide sequence. Purified IgG was prepared by affinity chromatography on Protein A. Target Species: Mouse |
Other Names | [delta-like protein 3 isoform 1; Delta-like protein 3; delta-like protein 3; delta3; drosophila Delta homolog 3; delta-like 3 (Drosophila); Drosophila Delta homolog 3; Delta3], [DLL3; DLL3; SCDO1; Delta3] |
Gene, Accession # | Gene ID: 10683, NCBI: NP_058637.1 |
Catalog # | MBS224287 |
Price | $375 |
Order / More Info | Mouse DELTA-LIKE PROTEIN 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |