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Antigenic Specificity | ERR alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Estrogen-related receptor alpha (ERRalpha/NR3B1) is an orphan nuclear receptor that controls transcription of genes involved in fatty acid oxidation, glucose metabolism, and mitochondrial biogenesis. The receptor protein contains a non-conserved amino terminal domain (NTD), a central zinc finger DNA binding domain, and a ligand-binding domain. The carboxy-terminal AF2 helix motif of ERRalpha contains binding sites for nuclear receptor coactivators PGC-1alpha and PGC-1beta. Research studies demonstrate that ERRalpha transcriptional activity is regulated through phosphorylation and sumoylation within the NTD. |
Immunogen | Immunogen: A synthesized peptide derived from human ERR alpha |
Other Names | [ESRRA; ERRa; ERR1; HERR1; NR3B1; Steroid hormone receptor ERR1; ERR-alpha; ERRalpha; ESRL1; Estrogen receptor-like 1; Estrogen-related receptor alpha] |
Gene, Accession # | [ERRalpha], Gene ID: 2101, NCBI: P11474.3, UniProt: P11474 |
Catalog # | MBS8542637 |
Price | $280 |
Order / More Info | ERR alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |