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Antigenic Specificity | MLK4 (N-term), 33-62 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MLK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human MLK4. Mixed-lineage kinases (MLKs) function as mitogen-activated protein kinase kinase kinases (MAP3Ks), activating the p38 and JNK signaling cascades. Systematic mutational analyses of tyrosine kinases reveal that a minimum of 30% of colorectal cancer contain at least one mutation in the tyrosine kinases; sampling of colorect cancer cells suggest an important role of MLK4 in this process. |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase MLK4; Mixed lineage kinase 4; MLK4 {ECO:0000303|Ref1}] |
Gene, Accession # | [MLK4], Gene ID: 84451, NCBI: NP_115811.2, UniProt: Q5TCX8 |
Catalog # | MBS9207722 |
Price | $165, $370 |
Order / More Info | MLK4 (N-term), 33-62 Antibody from MYBIOSOURCE INC. |
Product Specific References | Gregory,S.G., Nature 441 (7091), 315-321 (2006) |