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Antigenic Specificity | Phospho-Sodium Potassium ATPase alpha 1 (Tyr260) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-ATP1 alpha1/Na+K+ ATPase1 (Tyr260) Antibody detects endogenous levels of ATP1 alpha1/Na+K+ ATPase1 only when phosphorylated at Tyr260. Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.Post Translational Modifications: Phosphorylation on Tyr-10 modulates pumping activity. Phosphorylation of Ser-943 by PKA modulates the response of ATP1A1 to PKC. Dephosphorylation by protein phosphatase 2A (PP2A) following increases in intracellular sodiu |
Immunogen | Immunogen: A synthesized peptide derived from human ATP1 alpha1/Na K ATPase1 around the phosphorylation site of Tyr260. |
Other Names | [ATPase Na+/K+ transporting alpha; adenosinetriphosphatase; AT1A1_HUMAN; ATP1A1; ATP1A4; ATP1AL2; ATP1B; ATP1B1; ATPase Na+/K+ transporting alpha 1 polypeptide; ATPase Na+/K+ transporting alpha 4 polypeptide; ATPase Na+/K+ transporting beta 1 polypeptide; ATPase, Na+/K+ transporting, alpha polypeptide-like 2; ATPase, Na+/K+ transporting, beta 1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; Na(+)/K(+) ATPase alpha-1 subunit; Na(+)/K(+) ATPase alpha-4 subunit; Na+, K+ ATPase alpha subunit; Na+/K+ ATPase 1; Na+/K+ ATPase 4; Na+/K+ ATPase, alpha-D polypeptide; Na, K-ATPase beta-1 polypeptide; Na, K-ATPase, alpha-A catalytic polypeptide; Na,K-ATPase catalytic subunit alpha-A protein; Na,K-ATPase subunit alpha-C; polypeptide-like 2; Sodium pump 1; sodium pump 4; Sodium pump subunit alpha-1; sodium pump subunit alpha-4; sodium pump subunit beta-1; sodium-potassium ATPase catalytic subunit alpha-1; sodium-potassium ATPase catalytic subunit alpha-4; sodium-potassium ATPase subunit beta 1 (non-catalytic); sodium-potassium ATPase, alpha 4 polypeptide; sodium-potassium-ATPase, alpha 1 polypeptide; Sodium/potassium transporting ATPase alpha 1 chain; Sodium/potassium transporting ATPase subunit beta 1; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-transporting ATPase alpha-4 chain; sodium/potassium-transporting ATPase beta-1 chain; Sodium/potassium-transporting ATPase subunit alpha-1; sodium/potassium-transporting ATPase subunit alpha-4] |
Gene, Accession # | Gene ID: 476, NCBI: NP_000692.2, UniProt: P05023 |
Catalog # | MBS9610562 |
Price | $225, $280, $340 |
Order / More Info | Phospho-Sodium Potassium ATPase alpha 1 (Tyr260) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |