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Antigenic Specificity | Caveolin-1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. |
Immunogen | Immunogen: A synthesized peptide derived from human Caveolin-1. Subcellular Localization: Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae. Tissue Specificity: Expressed in muscle and lung, less so in liver, brain and kidney. |
Other Names | [Caveolin-1; CAV1; CAV], [CAV1; CAV1; CGL3; PPH3; BSCL3; LCCNS; VIP21; MSTP085; CAV] |
Gene, Accession # | [CAV1], Gene ID: 857, NCBI: NP_001744.2, UniProt: Q03135 |
Catalog # | MBS179168 |
Price | $160, $340, $340 |
Order / More Info | Caveolin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |