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Antigenic Specificity | Human Oxysterols receptor LXR-alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism. |
Immunogen | Immunogen: Recombinant human Oxysterols receptor LXR-alpha protein |
Other Names | [Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3; NR1H3; LXRA] |
Gene, Accession # | Gene ID: 10062, NCBI: NP_001123573.1, UniProt: Q13133 |
Catalog # | MBS7001745 |
Price | $160, $235 |
Order / More Info | Human Oxysterols receptor LXR-alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |