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Antigenic Specificity | Caspase-9 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse, rat, other |
Isotype | IgG |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of C6 cells (rat), untreated or treated with staurosporine or cytochrome c as indicated, using caspase-9 antibody. Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family (1, 2). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Another cleavage occurs at Asp330 producing a p37 subunit that can serve to amplify the apoptotic response (3-6). Cleaved caspase-9 further processes other caspase members, including caspase-3 and caspase-7, to ini |
Immunogen | Immunogen: Recombinant protein of human Caspase-9 |
Other Names | [caspase-9; Caspase-9; caspase-9; caspase 9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3] |
Gene, Accession # | Gene ID: 842, NCBI: BAA87905.1 |
Catalog # | MBS4150059 |
Price | $385 |
Order / More Info | Caspase-9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |