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Antigenic Specificity | Focal Adhesion Kinase (pTyr576/pTyr577) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti focal adhesion kinase (pTyr576/pTyr577) antibody recognizes focal adhesion kinase, also known as FAK, when phosphorylated at tyrosine 576/ tyrosine 577. Focal adhesion kinase is a highly conserved tyrosine kinase with roles in several biological processes including adhesion, migration and cell survival. FAK consists of four domains, an N-terminal FERM domain; a catalytic tyrosine kinase domain; a C-terminal focal-adhesion targeting (FAT) domain and an unstructured proline rich region between the catalytic and FAT domains. Phosphorylation of FAK at tyrosine 576/577 by Src leads to an increase in the kinase activity of FAK. |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding tyrosine 576/ tyrosine 577 of human focal adhesion kinase |
Other Names | [Focal Adhesion Kinase (pTyr576/pTyr577)], [PTK2; PTK2; FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK; FAK; FAK1; FADK 1; FRNK; PPP1R71] |
Gene, Accession # | [PTK2], Gene ID: 5747, NCBI: Q05397.2, UniProt: Q05397 |
Catalog # | MBS225251 |
Price | $375 |
Order / More Info | Focal Adhesion Kinase (pTyr576/pTyr577) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |