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Antigenic Specificity | alpha 5 beta 1 Integrin [M200 (Volociximab)] |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.2 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Block, Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody binds to human a5beta1 integrin with a Kd of 0.367 nM (determined by Biacore), an EC50 of 0.2 nM and an IC50 of 2.3 nM. Recombinant monoclonal antibody to alpha 5 beta 1 Integrin. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the hybridoma M200 (Volociximab). NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques. |
Immunogen | Immunogen: Heterodimeric a5beta1Fc Chimeric Use Statement: NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS488198 |
Price | $425 |
Order / More Info | alpha 5 beta 1 Integrin [M200 (Volociximab)] Antibody from MYBIOSOURCE INC. |
Product Specific References | Ramakrishnan et al. Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent. J Exp Ther Oncol. 2006; 5(4):273-86. PMID:17024968 |