Edit |   |
---|---|
Antigenic Specificity | Human CD230 (N-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | bovine, hamster, sheep |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistology Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti Human CD230 antibody recognizes human Major prion protein, also known as PrP27-30, CD230, or PrP33-35C. CD230 is a 253 amino acid ~27 kDa GPI anchored membrane protein. CD230 is found in large amounts in the brain of patients with transmissible spongiform encephalopathies (TSEs) or prion diseases, fatal infectious neurodegenerative diseases of humans and animals. These diseases are biologically unique, as they are believed by some to be transmitted by an infectious agent comprised only of protein, with no nucleic acid component. Clinically, these diseases present with motor disturbances and behavioural changes. The major pathological changes seen are neuronal loss, vacuolation (spongiform change), proliferation and branching of gl |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 79-97 of the N-terminus of human prion protein Histology Positive Control Tissue: CJD brain Antiserum Preparation: Antisera to human PrP27-30 were raised by repeated immunisation of goats with highly purified antigen. Target Species: Human |
Other Names | [major prion protein preproprotein; Major prion protein; alternative prion protein; major prion protein; CD230 antigen; prion-related protein; prion protein; ASCR; PrP27-30; PrP33-35C; CD_antigen: CD230], [PRNP; PRNP; CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C; ALTPRP; PRIP; PRP; PrP] |
Gene, Accession # | [CD230], Gene ID: 5621, NCBI: NP_000302.1, UniProt: P04156 |
Catalog # | MBS222420 |
Price | $550 |
Order / More Info | Human CD230 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |