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Antigenic Specificity | Presenilin 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Frozen |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. |
Immunogen | Immunogen: Presenilin 2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human Presenilin-2, different from the related Rabbit and rat sequences by two amino acids, as the immunogen |
Other Names | [Affinity Purified Goat Presenilin 2; Presenilin 2; Presenilin 2; PS2; Presenilin-2; Presenilin -2; Presenilin 2; PS-2; Presenilin 2; Presenilin -2; Presenilin 2] |
Gene, Accession # | [PSEN2] |
Catalog # | MBS5312689 |
Price | $345 |
Order / More Info | Presenilin 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |