Tau (Phospho-Ser214) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTau (Phospho-Ser214)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatepitope affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous level of Tau only when phosphorylated at serine 214. Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
ImmunogenImmunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 214 (T-P-S(p)-L-P) derived from Human Tau.
Other Names[MAPT; MTAPT; MTBT1; Neurofibrillary tangle protein; PHF-tau]
Gene, Accession #[Tau], Gene ID: 4137, NCBI: NP_001116538.2, UniProt: P10636
Catalog #MBS9400689
Price$200, $255
Order / More InfoTau (Phospho-Ser214) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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