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Antigenic Specificity | HLA-ABC (MHC I) |
Clone | [SPM419] |
Host Species | Mouse |
Reactive Species | human, mouse, nonhuman primates |
Isotype | IgG2a, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. |
Immunogen | Immunogen: Human peripheral blood leukocytes |
Other Names | [HLA-A; HLA-B; HLA-C; HLA class 1A; HLA class 1B; HLA class 1C; Major histocompatibility complex, class I, A + B + C; MHC class I HLA-A; MHC class I HLA-B; MHC class I HLA-C; MHC HLA-ABC], [HLA-B; HLA-C] |
Gene, Accession # | [HLA-A], Gene ID: 3106, NCBI: NP_005505.2, UniProt: P01889 |
Catalog # | MBS439211 |
Price | $190, $340, $340 |
Order / More Info | HLA-ABC (MHC I) Antibody from MYBIOSOURCE INC. |
Product Specific References | Young NT et al. Killer cell inhibitory receptor interactions with HLA class I molecules: implications for alloreactivity and transplantation. Hum Immunol 1997, 52(1):1-11 Krensky AM et al Immunomodulation by HLA class I-derived peptides. Transplant Proc 1996, 28(6):3026-8 Hansen JA et al The HLA system in clinical marrow transplantation. Hematol Oncol Clin North Am 1990, 4(3):507-515. |