Edit |   |
Antigenic Specificity | Angiotensinogen |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit IgG polyclonal antibody for Angiotensinogen(AGT) detection. Background: AGT(ANGIOTENSINOGEN), also called SERPINA8, is an alpha-2-globulin that is produced constitutively and released into the circulation mainly by the liver. ATG is a member of the serpin family, although it is not known to inhibit other enzymes, unlike most serpins. Angiotensinogen is also known as renin substrate. The AGT gene is mapped on 1q42.2. And the human angiotensinogen gene contains 5 exons. The expression of AGT and enzymes required for its conversion to angiotensin II in human adipose tissue. Mutations in this AGT gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular d |
Immunogen | Immunogen: E Coli-derived mouse Angiotensinogen recombinant protein (Position: D25-A115). Mouse Angiotensinogen shares 62.2% and 87.9% amino acid (aa) sequence identity with human and rat Angiotensinogen, respectively. |
Other Names | [AGT; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-1; Angiotensin-2; Angiotensin-3; Angiotensinogen; ANGT; ANHU; P01019; Pre angiotensinogen; Serpin A8; SERPINA8; angiotensinogen (serpin peptidase inhibitor, clade A, member 8)], [Agt; Agt; AngI; AngII; Aogen; AI265500; Serpina8; Serpina8; Ang I; Ang II; Ang III; Ang IV] |
Gene, Accession # | [AGT], Gene ID: 11606, NCBI: P11859.1, UniProt: P11859 |
Catalog # | MBS178661 |
Price | $315 |
Order / More Info | Angiotensinogen Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Abonia, J. P., Abel, K. J., Eddy, R. L., Elliott, R. W., Chapman, V. M., Shows, T. B., Gross, K. W. Linkage of Agt and Actsk-1 to distal mouse chromosome 8 loci: a new conserved linkage. Mammalian Genome 4: 25-32, 1993.2. Arakawa, K., Minohara, A., Yamada, J., Nakamura, M. Enzymatic degradation and electrophoresis of human angiotensin I. Biochim. Biophys. Acta 168: 106-112, 1968.3. Basso N, Terragno NA (December 2001). History about the discovery of the renin-angiotensin system. Hypertension 38 (6): 1246-9. |