Phospho-PYK2(Tyr580) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-PYK2(Tyr580) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-PYK2(Tyr580) antibody detects endogenous levels of PYK2 only when phosphorylated at Tyrosine 580. Description: Pyk2 a nonreceptor tyrosine kinase of the Fak family. Predominantly expressed in the cells derived from hematopoietic lineages and in the central nervous system. Pyk2 is one of the signaling mediators for G-protein-coupled receptors. Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. Interacts with the SH2 domain of Grb2.Function: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune res |
| Immunogen | Immunogen: A synthesized peptide derived from human PYK2 around the phosphorylation site of Tyrosine 580 Subcellular Location: Cytoplasm. Cell Membrane. Interaction with nephrocystin induces the membrane-association of the kinase. Tissue Specificity: Most abundant in the brain, with highest levels in amygdala and hippocampus. Low levels in kidney (at protein level). Also expressed in spleen and lymphocytes. |
| Other Names | [CADTK; CAK-beta; CAKB; CAKbeta; Calcium regulated non receptor proline rich tyrosine kinase; Calcium-dependent tyrosine kinase; Cell adhesion kinase beta; E430023O05Rik; EC 2.7.10.2; FADK 2; FADK2; FAK2; FAK2_HUMAN; Focal adhesion kinase 2; MGC124628; PKB; Proline-rich tyrosine kinase 2; Protein kinase B; Protein Tyrosine Kinase 2 Beta; Protein-tyrosine kinase 2-beta; PTK; PTK2B; PTK2B protein tyrosine kinase 2 beta; PYK2; RAFTK; RAFTK2; Related adhesion focal tyrosine kinase] |
| Gene, Accession # | [PYK2], Gene ID: 2185, NCBI: NP_004094.3, UniProt: Q14289 |
| Catalog # | MBS9600007 |
| Price | $240, $280 |
| Order / More Info | Phospho-PYK2(Tyr580) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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