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Antigenic Specificity | (Mouse) Sox2 (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Sox2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 34-68 amino acids from the N-terminal region of mouse Sox2. Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
Immunogen | n/a |
Other Names | [Transcription factor SOX-2; Sox2; Sox-2] |
Gene, Accession # | [Sox2], Gene ID: 20674, NCBI: NP_035573.3, UniProt: P48432 |
Catalog # | MBS9211721 |
Price | $165, $370 |
Order / More Info | (Mouse) Sox2 (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Yuan H.,et al.Genes Dev. 9:2635-2645(1995). Yuan H.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases. Collignon J.,et al.Development 122:509-520(1996). Tsuruzoe S.,et al.Biochem. Biophys. Res. Commun. 351:920-926(2006). Takahashi K.,et al.Cell 126:663-676(2006). |