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Antigenic Specificity | RHOB - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, goat, guinea pig, horse, human, mouse, porcine, rabbit, rat, sheep, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against RHOB. It was validated on Western Blot using a cell lysate as a positive control.Target Description: RHOB mediates apoptosis in neoplastically transformed cells after DNA damage.RHOB is not essential for development but affects cell adhesion and growth factor signaling in transformed cells.RHOB plays a negative role in tumorigenesis as deletion causes tumor formation. RHOB is involved in intracellular protein trafficking of a number of proteins.RHOB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.RHOB is also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular deve |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RHOB |
Other Names | [rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoB; rho-related GTP-binding protein RhoB; ras homolog family member B; Rho cDNA clone 6] |
Gene, Accession # | [RHOB], Gene ID: 388, NCBI: NP_004031, UniProt: P62745 |
Catalog # | MBS3211811 |
Price | $365 |
Order / More Info | RHOB - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |