Edit |   |
---|---|
Antigenic Specificity | GABAA R alpha1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GABAA R alpha1 antibody detects endogenous levels of total GABAA R alpha1. Function: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).Subunit Structure: Heteropentamer, formed by a combination of alpha, beta, gamma, delta and rho chains. Interacts with UBQLN1. Interacts with TRAK1. Interacts with KIF21B.Similarity: Belongs to the ligand-gated ion channel (TC 1.A.9) fam |
Immunogen | Immunogen: A synthesized peptide derived from human GABAA R alpha1 Subcellular Location: Cell Junction > Synapse > Postsynaptic Cell Membrane. Cell Membrane. |
Other Names | [ECA4; EIEE19; EJM; EJM5; Gaba receptor alpha 1 polypeptide; GABA(A) receptor; GABA(A) receptor subunit alpha 1; GABA(A) receptor subunit alpha-1; GABA(A) receptor, alpha 1; GABRA 1; GABRA1; Gamma aminobutyric acid (GABA) A receptor alpha 1; Gamma aminobutyric acid A receptor alpha 1; Gamma aminobutyric acid receptor subunit alpha 1; Gamma aminobutyric acid type A receptor alpha1 subunit; Gamma-aminobutyric acid receptor subunit alpha-1; GBRA1_HUMAN] |
Gene, Accession # | [GABRA1], Gene ID: 2554, NCBI: NP_000797.2, UniProt: P14867 |
Catalog # | MBS9608865 |
Price | $240, $280 |
Order / More Info | GABAA R alpha1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |