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Antigenic Specificity | HOMER2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. |
Immunogen | n/a |
Other Names | [homer protein homolog 2 isoform 2; Homer protein homolog 2; homer protein homolog 2; cupidin; homer homolog 2; homer homolog 3; homer, neuronal immediate early gene, 2; homer scaffolding protein 2; Cupidin], [HOMER2; HOMER2; CPD; ACPD; VESL-2; HOMER-2] |
Gene, Accession # | [HOMER2], Gene ID: 9455, NCBI: NP_955362.1 |
Catalog # | MBS416817 |
Price | $230 |
Order / More Info | HOMER2 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Nicolas,E., Poitelon,Y., Chouery,E., et al. CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592. Eur. J. Hum. Genet. 18 (10), 1107-1113 (2010) |