SOCS1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SOCS1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg |
| Concentration | 0.5 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: The Suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins that regulate responses to cytokines. SOCS1 suppresses dendritic cell and T cell hyperactivation in response to cytokine signaling by inhibiting the JAK tyrosine kinase. JAK tyrosine kinase activity is important for type I and II cytokine receptors to initiate signaling, and its activity is inhibited by direct binding of SOCS1 to the catalytic domain of the kinase. SOCS1 also has E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome. |
| Immunogen | Immunogen: Synthetic peptide surrounding amino acid 196 of rat SOCS1 |
| Other Names | [CIS1,CISH1; JAB; JAK binding protein; SOCS-1; SOCS1,SSI-1; SSI1; TIP3], [Socs1; Socs1; Cish1; Socs-1; SOCS-1] |
| Gene, Accession # | [SOCS1], Gene ID: 252971, NCBI: Q9QX78.1, UniProt: Q9QX78 |
| Catalog # | MBS840728 |
| Price | $150, $290 |
| Order / More Info | SOCS1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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