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Antigenic Specificity | TLR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Toll like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL 1 receptor motif in the cytoplasmic domain. Up to date, ten TLRs (TLR1 10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B cells. CD3+ T cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types is regulated by different immune response modifiers. For example, LPS, GM CSF, IL 1, and IL 10 up regulate TLR2, whereas IL 4, IFN gamma, and TNF down regulate TLR2 expression in monocytes. |
Immunogen | Immunogen: TLR2 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 753 of mouse TLR2 as the immunogen. |
Other Names | [Rabbit TLR2; TLR2; TLR2; TLR-2; Toll like receptor 2; TLR2; TLR 2; TLR-2; TLR 2; TLR-2] |
Gene, Accession # | [TLR2], NCBI: ATD82882.1 |
Catalog # | MBS5309134 |
Price | $705 |
Order / More Info | TLR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |