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Antigenic Specificity | OGG1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: OGG1 antibody detects endogenous levels of total OGG1. Description: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for th |
Immunogen | Immunogen: A synthesized peptide derived from human OGG1 Subcellular Location: Mitochondrion; Nucleus and Nucleus > Nucleoplasm. Nucleus Speckle. Nucleus Matrix. Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Bovine, Sheep, Dog Similarity: Bovine (85%), Sheep (85%), Dog (91%) |
Other Names | [8 hydroxyguanine DNA glycosylase; 8 oxoguanine DNA glycosylase 1; 8 oxoguanine DNA glycosylase; AP lyase; DNA (apurinic or apyrimidinic site) lyase; DNA apurinic or apyrimidinic site lyase; DNA lyase; DNA-(apurinic or apyrimidinic site) lyase; HMMH; HOGG 1; HOGG1; MMH; MUTM; N glycosylase; Ogg 1; Ogg1; OGG1_HUMAN; OGH 1; OGH1] |
Gene, Accession # | [OGG1], Gene ID: 4968, NCBI: NP_002533.1, UniProt: O15527 |
Catalog # | MBS9607058 |
Price | $240, $280 |
Order / More Info | OGG1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |