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Antigenic Specificity | TrkB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for BDNF/NT-3 growth factors receptor(NTRK2) detection. Tested with WB in Human, Mouse, Rat. Background: Neurotrophic tyrosine kinase, receptor, type 2, also known as BDNF/NT-3 growth factors receptor or TrkB receptor, is a protein that in humans is encoded by the NTRK2 gene. The TrkB receptor is part of the large family of receptor tyrosine kinases. This gene is mapped to 9q21.33. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding di |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TrkB (70-90aa EIFIANQKRLEIINEDDVEAY), different from the related mouse and rat sequences by one amino acid. |
Other Names | [BDNF/NT-3 growth factors receptor; neurotrophic tyrosine kinase, receptor, type 2; AI848316; BDNF tropomyosine receptor kinase B; BDNF/NT 3 growth factors receptor; BDNF/NT-3 growth factors receptor; Brain derived neurotrophic factor receptor; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; Neurotrophic tyrosine kinase receptor type 2; Neurotrophin receptor tyrosine kinase type 2; NTRK 2; NTRK2; NTRK2_HUMAN; Obesity, hyperphagia, and developmental delay, included; RATTRKB1; Tkrb; Trk B; Trk-B; TRKB; TrkB tyrosine kinase; TRKB1; Tropomyosin related kinase B; tyrosine kinase receptor B; Tyrosine receptor kinase B], [NTRK2; NTRK2; TRKB; trk-B; GP145-TrkB; TRKB; Trk-B] |
Gene, Accession # | [NTRK2], Gene ID: 4915, NCBI: Q16620.1, UniProt: Q16620 |
Catalog # | MBS176346 |
Price | $280 |
Order / More Info | TrkB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |