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Antigenic Specificity | CD138, Syndecan-1 (B-A38) |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human. |
Isotype | n/a |
Format | unconjugated |
Size | 5 mL, 1 mL |
Concentration | 50 ug/ml |
Applications | Immunohistochemistry (IHC) Formalin/Paraffin, Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody B-A38 (like B-B4) stains all plasma cells and all plasma cell lines, which have been tested so far. No other leukocytes are stained in peripheral blood or bone marrow. However, some ALL cell lines express CD138 weekly, and some epithelia and endothelia may be stained in immunohistochemistry. Syndecan 1, CD138, is a heparan-rich glycoprotein (MW 200 kDa), which is expressed on the cell membrane of plasma cells. CD138 functions as a receptor for extracellular matrix proteins like collagen, fibronectin and thrombospondin. Human CD138, Syndecan 1. |
Immunogen | Immunogen: U266 cell line |
Other Names | n/a |
Gene, Accession # | [CD138] |
Catalog # | MBS397043 |
Price | $280, $505 |
Order / More Info | CD138, Syndecan-1 (B-A38) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Borset M., et al. (1993) Lack of IL-1 secretion from human myeloma cells highly purified by immunomagnetic separation. Br. J. Haem. 85; 446 ff. 2. Wijdenes J., et al. (1996) A plasmocyte selective monoclonal antibody (B-B4) recognises Syndecan-1. Br. J. Haem. 94; 318-323. 3. Inki. P. and Jalkanen M. (1996) The role of syndecan-1 in malignancies. Ann. Med. 28(1); 63-67. 4. Anttonen A., et al. (1999) Syndecan-1 expression has prognostic significance in head and neck carcinoma. Brit J. Cancer 79; 558-564. 5. Yang Y, MacLeod V, Dai Y, Khotskaya-Sample Y, Shriver Z, Venkataraman G,Sasisekharan R, Naggi A, Torri G, Casu B, Vlodavsky I, Suva LJ, Epstein J,Yaccoby S, Shaughnessy JD Jr, Barlogie B, Sanderson RD. (2007) The syndecan-1 heparan sulfate proteoglycan. |