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Antigenic Specificity | Urokinase Plasminogen Activator Receptor |
Clone | [10K37] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2A |
Format | Protein G purified |
Size | 100 tests |
Concentration | 0.025 mg/ml |
Applications | Western Blot and Flow Cytometry. Other applications not tested. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes mouse uPAR. No crossreactvity with recombinant human uPAR in Western Blot. CD87, a 45- to 60kD protein, consists of three structurally homologous domains of ~90aa, designated D1, D2, and D3, each containing a conserved arrangement of disulfide bonds and separated by short interdomain linker sequences. uPAR exists in various molecular forms; heavily glycosylated, a cleaved form, a soluble form and spliced forms. CD87 is expressed by monocytes/macrophages, neutrophils, endothelial, smooth muscle cells and epithelial cells. CD87 is overexpressed upon exposure to inflammatory mediators. The protein is also highly expressed by tumor cells and contributes to their invasiveness and metastatic potential. CD87 is a multiligand receptor th |
Immunogen | Immunogen: Recombinant protein corresponding to Leu24-Thr297 from mouse uPAR expressed in NS0 cells. UniProt Accession: P35456. |
Other Names | Urokinase Plasminogen Activator Receptor (U Plasminogen Activator Receptor, UPA Receptor, uPAR, U-PAR, CD87, CD87 Antigen, MO3, Monocyte Activation Antigen Mo3, Plasminogen Activator Urokinase Receptor, PLAUR, URKR) (PE) |
Gene, Accession # | Gene ID: 5329, UniProt: Q03405 |
Catalog # | MBS632008 |
Price | $670 |
Order / More Info | Urokinase Plasminogen Activator Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |