FAS ligand Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | FAS ligand |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: FAS ligand antibody detects endogenous levels of total FAS ligand. Function: Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:26334989, PubMed:9228058). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:9228058, PubMed:7528780, PubMed:9427603). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (By similarity). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (By similarity). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (PubMed:27806260).Subunit St |
| Immunogen | Immunogen: A synthesized peptide derived from human FAS ligand Subcellular Location: Cell Membrane. Secreted. May be released into the extracellular fluid, probably by cleavage form the cell surface. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (100%), Bovine (86%), Horse (88%), Sheep (86%), Dog (88%) |
| Other Names | [ALPS1B; Apoptosis (APO 1) antigen ligand 1; Apoptosis antigen ligand 1; Apoptosis antigen ligand; APT1LG1; APTL; CD178; CD178 antigen; CD95 ligand; CD95-L; CD95L; CD95L protein; Fas antigen ligand; Fas L; Fas ligand (TNF superfamily member 6); Fas ligand; FASL; Fasl Fas ligand (TNF superfamily member 6); FASLG; Generalized lymphoproliferative disease; Gld; soluble form; TNFL6_HUMAN; TNFSF6; Tumor necrosis factor (ligand) superfamily member 6; Tumor necrosis factor ligand superfamily member 6] |
| Gene, Accession # | [FASLG], Gene ID: 356, NCBI: NP_000630.1, UniProt: P48023 |
| Catalog # | MBS9601505 |
| Price | $240, $280 |
| Order / More Info | FAS ligand Antibody from MYBIOSOURCE INC. |
| Product Specific References | Qian P, Zhang YW, Zhou ZH, Liu JQ, Yue SY, Guo XL, Sun LQ, Lv XT, Chen JQ; Journal: Immunopharmacol Immunotoxicol. Artesunate enhances T-cell-mediated antitumor activity through augmenting T-cell function and reversing immune escape of HepG2 cells. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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