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Antigenic Specificity | TRAIL-R2 (Human) |
Clone | [DJR2-4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human TRAIL-R2. DR5 is 55kDa member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262. It binds the cytotoxic ligand TRAIL and induces apoptosis. The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors. DR5 expression has been reported to be upregulated in human cells by interferon- alpha, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins. |
Immunogen | Immunogen: Recombinant human TRAIL-R2 extracellular domain IgG1 Fc fusion protein. |
Other Names | [TRAIL receptor 2; DR5; Death receptor 5; KILLER; CD262; Trick2; Ly98; TNFRSF10B; TNF-related apoptosis-inducing ligand receptor 2; Tumor necrosis factor receptor superfamily member 10B], [TNFRSF10B; TNFRSF10B; DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; TRAIL receptor 2; TRAIL-R2] |
Gene, Accession # | [TRAIL-R2], Gene ID: 8795, NCBI: O14763.2, UniProt: O14763 |
Catalog # | MBS565006 |
Price | $295 |
Order / More Info | TRAIL-R2 (Human) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |