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Antigenic Specificity | Human ADRA1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | gorilla, human, monkey. predicted reactivity: bovine (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human ADRA1B. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SLC22A3 (50%). The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. |
Immunogen | Immunogen Description: Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human ADRA1B. Percent identity with other species by BLAST analysis: Human, Gorilla, Marmoset (100%); Bovine (94%); Monkey, Mouse, Rat, Hamster, Elephant, Dog (88%). |
Other Names | [ADRA1B (Cytoplasmic Domain) IHC-plus; ADRA1B; Alpha 1b; Alpha-1B adrenergic receptor; Alpha-1b-adrenergic; Alpha-1B-adrenergic receptor; Alpha1b; Adrenoceptor alpha 1B; Alpha-1B adrenoreceptor; Alpha1B-AR; Alpha1beta-AR; ALPHA1BAR; ADRA1; Alpha-1B adrenoceptor; Alpha1b-adrenergic; Human ADRA1B], [ADRA1B; ADRA1B; ADRA1; ALPHA1BAR; Alpha-1B adrenoceptor] |
Gene, Accession # | [ADRA1B], Gene ID: 147, NCBI: NP_000670.1, UniProt: P35368 |
Catalog # | MBS247966 |
Price | $530 |
Order / More Info | Human ADRA1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |