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Antigenic Specificity | Caspase 8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The affinity purified antibody mainly detects the 26 kDa fully cleaved fragment and the 35-43 kDa intermediate of Caspase-8 in apoptotic samples. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro enzyme. Activation of Caspase 8 involves a two step proteolysis: the cleavage of Caspase 8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18. |
Immunogen | Immunogen: Caspase 8 antibody was raised in Rabbit using synthetic peptide surrounding the cleavage site of human Caspase-8 as the immunogen. |
Other Names | [Rabbit Caspase 8; Caspase 8; Caspase 8; Caspase-8; Cysteine-Aspartic Acid Protease 8; Caspase 8; Caspase 8; Caspase-8; Caspase 8; Caspase-8] |
Gene, Accession # | Gene ID: 841 |
Catalog # | MBS5309066 |
Price | $705 |
Order / More Info | Caspase 8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |