Caspase 8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase 8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration500 ug/ml
ApplicationsWestern Blot (WB)
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DescriptionThe affinity purified antibody mainly detects the 26 kDa fully cleaved fragment and the 35-43 kDa intermediate of Caspase-8 in apoptotic samples. Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase 8 is a 55 kDa cytosolic protein that is synthesized as an inactive pro enzyme. Activation of Caspase 8 involves a two step proteolysis: the cleavage of Caspase 8 to generate a 43 and a 12 kDa fragment which is further processed to 10 kDa. The p43 is then cleaved to yield p26 and the release of the active site containing p18.
ImmunogenImmunogen: Caspase 8 antibody was raised in Rabbit using synthetic peptide surrounding the cleavage site of human Caspase-8 as the immunogen.
Other Names[Rabbit Caspase 8; Caspase 8; Caspase 8; Caspase-8; Cysteine-Aspartic Acid Protease 8; Caspase 8; Caspase 8; Caspase-8; Caspase 8; Caspase-8]
Gene, Accession #Gene ID: 841
Catalog #MBS5309066
Price$705
Order / More InfoCaspase 8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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