Edit |   |
---|---|
Antigenic Specificity | CTCF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total CTCF antibody. CCCTC-binding factor (CTCF) and its paralog, the Brother of the Regulator of Imprinted Sites (BORIS), are highly conserved transcription factors that regulate transcriptional activation and repression, insulator function, and imprinting control regions (ICRs) (1-4). Although they have divergent amino and carboxy termini, both proteins contain 11 conserved zinc finger domains that work in combination to bind the same DNA elements (1). CTCF is ubiquitously expressed and contributes to transcriptional regulation of cell-growth regulated genes, including c-myc, p19/ARF, p16/INK4A, BRCA1, p53, p27, E2F1, and TERT (1). CTCF also binds to and is required for the enhancer-blocking activi |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human CTCF. |
Other Names | [CTCF] |
Gene, Accession # | [CTCF], Gene ID: 10664, NCBI: NP_001177951.1, UniProt: P49711 |
Catalog # | MBS9404028 |
Price | $255 |
Order / More Info | CTCF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |