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Antigenic Specificity | BRD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bromodomain-containing protein 4 (BRD4) is a member of the bromodomairls and extraterminal (BET) family of proteins, which also includes BRD2, BRD3, and BRDT (1-3). BET family proteins contain two tandem bromodomains and an extra terminal (ET) domain, and bind acetyl lysine residues (3). BRD4 is a chromatin-binding protein with a preference for Lys14 on histone H3 as well as Lys5 and Lys12 on histone H4 (4). BRD4 chromatin binding occurs throughout the cell cycle, including condensed mitotic chromosomes, when the majority of genes are silenced (5). DRD4 tlssocia::oll with chromatin uuring mitosis is thought to be an important part of the bookmarking mechanism to accelerate re-activation of the silenced genes upon exit from mitosis (2,6). BR |
Immunogen | n/a |
Other Names | [BRD4], [BRD4; BRD4; CAP; MCAP; HUNK1; HUNKI; HUNK1] |
Gene, Accession # | Gene ID: 23476, NCBI: NP_055114.1, UniProt: O60885 |
Catalog # | MBS126660 |
Price | $200, $275, $430 |
Order / More Info | BRD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |