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Antigenic Specificity | Phospho-LCK (Tyr394) |
Clone | [5C6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB); Immunoprecipitation (IP); ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal antibody to detect Lck (Phospho-Tyr394) in human samples. Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in some murine lymphomas. In human studies; it has been demonstrated that the Lck gene is localized to a site in the genome which undergoes frequent chromosomal abnormalities in lymphomas and neuroblastomas. Resting T cells contain high levels of the Lck protein and mRNA both of which decline upon activation of the T cells. These and other observations smuggest that alterations in Lck expression may contribute to the pathogenesis of some types of neoplastic disease. |
Immunogen | n/a |
Other Names | [LCK; p56-LCK; p56lck; YT16; pp58lck; LSK], [LCK; LCK; LSK; YT16; IMD22; p56lck; pp58lck; LSK] |
Gene, Accession # | [LCK], Gene ID: 3932, NCBI: NP_001036236.1, UniProt: P06239 |
Catalog # | MBS845905 |
Price | $345 |
Order / More Info | Phospho-LCK (Tyr394) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |