Mcl-1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Mcl-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | serum |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes Mcl-1, isoforms 1 and 2. Human Mcl-1 isoform 1 is a 350 amino acid protein. Bcl2 family members can be divided into 3 main subfamilies on the basis of their function and the content of their Bcl2 homology (BH) domains, for example: 1) Prosurvival: Bcl-2, BclXL, BclW, A1, and Mcl-1and 2) Proapoptotic (multidomain): Bax, Bak, and Bok. 3) BH3-only (proapoptotic): Bad, Bcl-XS, Bid, Bik, Bim, Blk, Bmf, Bnip, Noxa, and Puma. The BH domains are important for function as well as for heterodimerization between family members. Typical prosurvival members have all four BH domains (1-4), whereas proapoptotic (multidomain) members have BH1, 2 and 3 domains and BH3-only members have only the BH3 domain. Overall, the relative rati |
| Immunogen | Immunogen Information: A synthetic peptide of human Mcl-1 (amino acids 121-139 SPEEELDGYEPEPLGKRPA) was used as immunogen for this antibody |
| Other Names | [MCL1; BCL2L3; Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; mcl1/EAT; to Mcl-1; Mcl-1; Mcl-1], [MCL1; MCL1; TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; BCL2L3; Bcl2-L-3] |
| Gene, Accession # | [MCL1], Gene ID: 4170, NCBI: Q07820.3, UniProt: Q07820 |
| Catalog # | MBS668710 |
| Price | $270 |
| Order / More Info | Mcl-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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