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Antigenic Specificity | TESC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 1.1 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TESC protein. Tescalcin, also known as TESC, TSC or CHP3, is a 267 amino acid protein that contains one EF-hand domain and is expressed abundantly in adult heart tissue. Using calcium as a cofactor, Tescalcin interacts with NHE-1 and functions to couple the activation of the ERK cascade with the expression of Ets proteins during megakaryocytic differentiation.Human Tescalcin shares 97% sequence identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoformsof Tescalcin exist due to alternative splicing events. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity.Promotes the maturation, transpor |
Immunogen | Immunogen: Fusion protein of human TESC |
Other Names | [TSC; CHP3] |
Gene, Accession # | [TESC], Gene ID: 54997, NCBI: NP_001161797.1, UniProt: Q96BS2 |
Catalog # | MBS9415369 |
Price | $255 |
Order / More Info | TESC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |