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Antigenic Specificity | ATF2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Peptide ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ATF2 Antibody can detect endogenous ATF2 protein. Not tested with other proteins. This gene encodes a highly conserved neurotrophic factor.The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection)protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutation |
Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
Other Names | [glial cell line-derived neurotrophic factor isoform 1 preproprotein; Glial cell line-derived neurotrophic factor; glial cell line-derived neurotrophic factor; ATF; astrocyte-derived trophic factor; glial cell derived neurotrophic factor; Astrocyte-derived trophic factor; ATF], [GDNF; GDNF; ATF1; ATF2; HSCR3; HFB1-GDNF] |
Gene, Accession # | [ATF2], Gene ID: 2668, NCBI: NP_000505 |
Catalog # | MBS415643 |
Price | $230 |
Order / More Info | ATF2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hoeffler,J.P., Lustbader,J.W. and Chen,C.Y Identification of multiple nuclear factors that interact with cyclic adenosine 3',5'-monophosphate response element-binding protein and activating transcription factor-2 by protein-proteininteractions |