VEGF Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | VEGF |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: VEGF antibody detects endogenous levels of total VEGF. Function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from |
| Immunogen | Immunogen: A synthesized peptide derived from human VEGF Subcellular Location: Secreted. VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding properties and, although a signicant proportion remains cell-associated, most is freely secreted. VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin. Tissue Specificity: Isoform |
| Other Names | [Folliculostellate cell-derived growth factor; Glioma-derived endothelial cell mitogen; MGC70609; MVCD1; Vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor; Vascular permeability factor; VEGF A; Vegf; VEGF-A; VEGF120; Vegfa; VEGFA_HUMAN; VPF] |
| Gene, Accession # | [VEGF], Gene ID: 7422, NCBI: NP_001020537.2, UniProt: P15692 |
| Catalog # | MBS9601304 |
| Price | $240, $280 |
| Order / More Info | VEGF Antibody from MYBIOSOURCE INC. |
| Product Specific References | Chen W, Chen J, Xu M, Zhong Z, Zhang Q, Yang W, Huang G; Journal: Biol Reprod. Electroacupuncture facilitates implantation by enhancing endometrial angiogenesis in a rat model of ovarian hyperstimulation. Wu CZ, Zheng JJ, Bai YH, Xia P, Zhang HC, Guo Y; Journal: Onco Targets Ther. HMGB1/RAGE axis mediates the apoptosis, invasion, autophagy, and angiogenesis of the renal cell carcinoma. Liu L, Chen L, Jiang C, Guo J, Xie Y, Kang L, Cheng Z; Journal: Exp Ther Med. Berberine inhibits the LPS-induced proliferation and inflammatory response of stromal cells of adenomyosis tissues mediated by the LPS/TLR4 signaling pathway. Li Q, Ma R, Zhang M; Journal: Oncol Lett. CoCl2 increases the expression of hypoxic markers HIF-1a, VEGF and CXCR4 in breast cancer MCF-7 cells. Yin LL, Wen XM, Lai QH, Li J, Wang XW; Journal: Oncol Lett. Lenalidomide improvement of cisplatin antitumor efficacy on triple-negative breast cancer cells in vitro. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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