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Antigenic Specificity | MAPK8 (C-term), 358-389 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Immunofluorescence (IF), ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAPK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human MAPK8. JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also invo |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK8; JNK1; PRKM8; SAPK1; SAPK1C] |
Gene, Accession # | [MAPK8], Gene ID: 5599, NCBI: NP_001265476.1, UniProt: P45983 |
Catalog # | MBS9201520 |
Price | $165, $370 |
Order / More Info | MAPK8 (C-term), 358-389 Antibody from MYBIOSOURCE INC. |
Product Specific References | Deng, Y., et al., Cell 115(1):61-70 (2003). Luo, W., et al., J. Biol. Chem. 278(39):37451-37458 (2003). Ghosh, J., Biochem. Biophys. Res. Commun. 307(2):342-349 (2003). Utsugi, M., et al., J. Immunol. 171(2):628-635 (2003). Vivo, C., et al., J. Biol. Chem. 278(28):25461-25467 (2003). |