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Antigenic Specificity | UBE2D1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:20061386). Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1 (PubMed:18042044, PubMed:18359941). Ubiquitinates STUB1-associated HSP90AB1 in vitro (PubMed:18042044). Lacks inherent specificity for any particular lysine residue of ubiquitin (PubMed:18042044). Essential for viral activation of IRF3 (PubMed:19854139). Mediates polyubiquitination of CYP3A4 (PubMed:19103148). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human UBE2D1 (NP 003329.1). |
Other Names | [SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1] |
Gene, Accession # | [UBE2D1], Gene ID: 7321, NCBI: P51668.1, UniProt: P51668 |
Catalog # | MBS8544694 |
Price | $280 |
Order / More Info | UBE2D1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |