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Antigenic Specificity | MIS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MIS protein. AMH encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig c |
Immunogen | Immunogen: Synthesized peptide derived from part region of human MIS protein at amino acid sequence of 380-460 |
Other Names | [Rabbit MIS; Muellerian hormone; AMH; Muellerian-inhibiting substance; MIS] |
Gene, Accession # | [MIS], Gene ID: 268, NCBI: NP_000470.2, UniProt: P03971 |
Catalog # | MBS9709836 |
Price | $130, $220, $325 |
Order / More Info | MIS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |