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Antigenic Specificity | ACE2 (SARS Receptor) (Center), 140-172 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ACE2 (SARS Receptor) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-172 amino acids from the Central region of human ACE2 (SARS Receptor). ACE2 cDNA encodes a deduced 805-amino acid protein containing a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It also possesses a zinc metalloprotease consensus sequence and a conserved glutamine residue that may function as a third zinc ligand. ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel con |
Immunogen | n/a |
Other Names | [Angiotensin-converting enzyme 2; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH; Metalloprotease MPROT15; Processed angiotensin-converting enzyme 2; ACE2] |
Gene, Accession # | [ACE2], Gene ID: 59272, NCBI: NP_068576.1, UniProt: Q9BYF1 |
Catalog # | MBS9204203 |
Price | $165, $370 |
Order / More Info | ACE2 (SARS Receptor) (Center), 140-172 Antibody from MYBIOSOURCE INC. |
Product Specific References | Douglas, G.C., et al., Endocrinology 145(10):4703-4711 (2004). Turner, A.J., et al., Trends Pharmacol. Sci. 25(6):291-294 (2004). Towler, P., et al., J. Biol. Chem. 279(17):17996-18007 (2004). Wong, S.K., et al., J. Biol. Chem. 279(5):3197-3201 (2004). Li, W., et al., Nature 426(6965):450-454 (2003). |